%0 Journal Article %A Masjedi, Fatemeh %A Gol, Ali %A Dabiri, Shahriar %A Javadi, Abdoreza %T Investigating the Preventive Effect of Garlic on Blood Glucose Levels and Histopathology of Pancreas in Streptozotocin-induced Diabetic Rats %J Physiology and Pharmacology %V 13 %N 2 %U http://ppj.phypha.ir/article-1-537-en.html %R %D 2009 %K Diabetes, Garlic, Pancreas, Histopahology, %X Introduction: The preventive antidiabetic effects of garlic juice on blood glucose levels and pancreas tissue was evaluated in STZ-induced diabetic rats. Methods: 40 male rats were divided into five groups of 8 rats each. 1) Normal group (N), 2) Normal+Garlic group (N+G) received 1 ml garlic juice/100g BW/day for 6 weeks, 3) Diabetic group (D) injected with streptozotocin (60 mg/kg BW,i.p.), 4) Diabetic + Garlic_before group (D+Gb) received garlic juice for 6 weeks, but at the end of third week, they were injected with STZ, 5) Diabetic+Garlic_after group (D+Ga) received garlic juice for 3 weeks, after they were injected with STZ. At the end of the experiment, serial sections of pancreas were prepared and stained with H&E for light microscope investigations. Results: Serum glucose levels were significantly increased (p %> http://ppj.phypha.ir/article-1-537-en.pdf %P 179-190 %& 179 %! %9 Experimental research article %L A-10-323-3 %+ %G eng %@ 24765236 %[ 2009