TY - JOUR JF - Physiol-Pharmacol JO - Physiol Pharmacol VL - 22 IS - 4 PY - 2018 Y1 - 2018/12/01 TI - Effectiveness of intravenous promethazine and diazepam in the treatment of peripheral vertigo in emergency department visits TT - N2 - Introduction: To improve our understanding of dizziness, its assessment, as well as its management to identify the appropriate treatment in order to reduce the costs and to increase the patients’ quality of life. Methods: A single blind parallel group randomized controlled trial was conducted on 164 participants with dizziness. One group received 25mg/ml promethazine and another received 5mg/ml diazepam. To assess the severity of dizziness, Visual Analog Scale was used prior to and two hours after treatment. Results: Both promethazine and diazepam had significant effects on decreasing the severity of dizziness, i.e. the severity score decreased from 9.31 to 1.81 in promethazine versus 9.33 to 4.50 in diazepam (P<0.001). Conclusion: A single IV dose of promethazine is more effective in reducing vertigo as compared with diazepam. SP - 213 EP - 218 AU - Fayyazi, Seyed Mohsen AU - Taghizadeh, Mehrdad AU - Nabizadeh-Gharghozar, Zohreh AU - Javadzadeh, Hamidreza AU - Mahmudi, Sadrollah AU - Heidari, Kamran AD - Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran KW - Diazepam KW - Dizziness KW - Promethazine KW - Vertigo KW - Vestibular UR - http://ppj.phypha.ir/article-1-1395-en.html ER -