fa Endocrine Physiology/Pharmacology Endocrine Physiology/Pharmacology Experimental research article Experimental research article <p dir="ltr" style="text-align: justify;"><span style="font-size: 12px;"><b>Introduction: </b><i><font face="Arial,Arial"><font face="Arial,Arial">Nymphea lotus </font></font></i><font face="Arial,Arial"><font face="Arial,Arial">Linn (</font></font><i><font face="Arial,Arial"><font face="Arial,Arial">N. lotus</font></font></i><font face="Arial,Arial"><font face="Arial,Arial">) flowers are used empirically for the treatment of male sexual disorders in Cameroon west region. This study was aimed to evaluate the effects of the </font></font><i><font face="Arial,Arial"><font face="Arial,Arial">N. lotus </font></font></i><font face="Arial,Arial"><font face="Arial,Arial">on some parameters of male fertility in adult albino male rats. </font></font></span><span style="font-size: 12px;"><b>Methods: </b><font face="Arial,Arial"><font face="Arial,Arial">twenty four male rats were divided in 4 groups (n=6 each) and subjected to the following treatment: distilled water as vehicle control (10 ml/kg), testosterone as reference drug (5 mg/kg) and </font></font><i><font face="Arial,Arial"><font face="Arial,Arial">N. lotus </font></font></i><font face="Arial,Arial"><font face="Arial,Arial">flowers aqueous extract at the doses of 75 (NL75) and 150 mg/kg (NL150). Distilled water and aqueous extract of the plant were given once daily whereas testosterone was injected intramuscularly once a week. Treatment lasted for 55 days. Index of libido, sperm count, motility and viability were assessed. Relative weight and histology of some androgens dependent organs were analyzed. </font></font></span><span style="font-size: 12px;"><b>Results: </b><font face="Arial,Arial"><font face="Arial,Arial">Our results showed the treatment with NL75 during 55 days, increased markedly the index of libido (83.33%) in animals compared to control (50%). Both </font></font><i><font face="Arial,Arial"><font face="Arial,Arial">N. lotus </font></font></i><font face="Arial,Arial"><font face="Arial,Arial">treated groups showed a significant elevation (</font></font><i><font face="Arial,Arial"><font face="Arial,Arial">P</font></font></i><font face="Arial,Arial"><font face="Arial,Arial"><0.05) of the sperm count compared to testosterone treated animals. NL75 and NL150 also induced a significant increase of the sperm motility (</font></font><i><font face="Arial,Arial"><font face="Arial,Arial">P</font></font></i><font face="Arial,Arial"><font face="Arial,Arial"><0.001; </font></font><i><font face="Arial,Arial"><font face="Arial,Arial">P</font></font></i><font face="Arial,Arial"><font face="Arial,Arial"><0.01). NL75 induced a considerable increase in sperm viability (66.35% vs. 50.11%) compared to control. Further, NL75 also improved significantly the relative weight of testis (</font></font><i><font face="Arial,Arial"><font face="Arial,Arial">P</font></font></i><font face="Arial,Arial"><font face="Arial,Arial"><0.05), prostate (</font></font><i><font face="Arial,Arial"><font face="Arial,Arial">P</font></font></i><font face="Arial,Arial"><font face="Arial,Arial"><0.001) and penis (</font></font><i><font face="Arial,Arial"><font face="Arial,Arial">P</font></font></i><font face="Arial,Arial"><font face="Arial,Arial"><0.05) compared to control, suggesting anabolic effects of our plant. </font></font></span><span style="font-size: 12px;"><b>Conclusion: </b><font face="Arial,Arial"><font face="Arial,Arial">From these findings, it was concluded that </font></font><i><font face="Arial,Arial"><font face="Arial,Arial">N. lotus </font></font></i><font face="Arial,Arial"><font face="Arial,Arial">flowers have androgenic and reproductive properties justifying its empirical uses.</font></font></span></p> Plants, Androgens, Testis, Fertility, Male rats 63 71 http://ppj.phypha.ir/browse.php?a_code=A-10-935-1&slc_lang=fa&sid=1 Kameni Poumeni Mireille my.kameni@gmail.com 3200319475328460017384 3200319475328460017384 Yes Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, Yaounde, Cameroon Dzeufiet Djomeni Paul Desire dzeufiet@yahoo.fr 3200319475328460017385 3200319475328460017385 No Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, Yaounde, Cameroon Bilanda Danielle Claude bilandad@yahoo.com 3200319475328460017386 3200319475328460017386 No Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, Yaounde, Cameroon Mengue Ngadena Yolande Sandrine ymenguengadena@yahoo.com 3200319475328460017387 3200319475328460017387 No Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, Yaounde, Cameroon Ngoungouré Madeleine Chantal mcngoun@yahoo.fr 3200319475328460017388 3200319475328460017388 No Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, Yaounde, Cameroon Mballa Marguerite Francine margfrance@yahoo.fr 3200319475328460017389 3200319475328460017389 No Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, Yaounde, Cameroon Mbolang Nguegan Lohik 3200319475328460017390 3200319475328460017390 No Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, Yaounde, Cameroon Dimo Theophile 3200319475328460017391 3200319475328460017391 No Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, Yaounde, Cameroon Kamtchouing Pierre pikam55@yahoo.fr 3200319475328460017392 3200319475328460017392 No Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, Yaounde, Cameroon