Physiology and Pharmacology
Physiol Pharmacol
Medical Sciences
http://ppj.phypha.ir
32
journal32
24765236
24765244
10.61186/phypha
(previous ISSN: 17350581)
en
jalali
1396
6
1
gregorian
2017
9
1
21
3
online
1
fulltext
en
A case of ciprofloxacin-associated Achilles tendinitis
Pharmacokinetics/Dynamics
Pharmacokinetics/Dynamics
Letter to the editor
Letter to the editor
<p dir="ltr" style="text-align: justify;"><span style="font-family: tahoma;"><span style="font-size: 12px;"><span style="font-family: tahoma;"><span style="font-size: 12px;">Achilles tendinitis is a rare adverse effect of the fluoroquinolone antibiotics. Fluoroquinolone antibiotics have widespread usage for treatment of Gram-negative-related infections particularly urinary tract and respiratory infections. Due to the prevalent usage of this family of antibiotics, it is necessary to be careful about their side effects including Achilles tendinitis, which can ensue tendon rupture. <span style="font-family: tahoma;"><span style="font-size: 12px;">This case report introduces an 84-year-old man diagnosed with Achilles tendinitis due to consumption of ciprofloxacin for treatment of urethritis. The patient experienced pain on posterior region of the left ankle after three days of antibiotic therapy onset and the pain was alleviated within a week following ciprofloxacin cessation along with treatment with nonsteroidal anti-inflammatory drugs. The Naranjo score was determined seven for this patient; accordingly, ciprofloxacin was the probable cause of this reaction. Early diagnosis of fluoroquinolones-associated Achilles tendinitis and stopping the treatment may prevent tendon rupture.</span></span></span></span></span></span></p>
Achilles Tendinitis, Ciprofloxacin, Fluoroquinolones
172
174
http://ppj.phypha.ir/browse.php?a_code=A-12-996-1&slc_lang=en&sid=1
Vahid
Pirhajati Mahabadi
Vpirhajati.1@gmail.com
3200319475328460018165
3200319475328460018165
No
Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran
Somayyeh
Nasiripour
nasiripours@yahoo.com
3200319475328460018166
3200319475328460018166
No
Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran
Maryam
Farasatinasab
maryfarasati@gmail.com
3200319475328460018167
3200319475328460018167
No
School of Pharmacy International Campus, Iran University of Medical Sciences, Tehran, Iran
Shabnam
Nadjafi
najafi.sh@iums.ac.ir
3200319475328460018168
3200319475328460018168
Yes
Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran