Physiology and Pharmacology

en The controllability of cardiac rhythm in elderly Cardiovascular Physiology/Pharmacology Cardiovascular Physiology/Pharmacology Short communication Short communication <div style="text-align: justify;">Introduction: Recent reports have shown that rare fluctuations in cardiac cycles are ‘forgotten’ quickly in healthy individuals and it is possible to quantify the “memory length” of a physiological time-series using an inverse statistical approach. Methods: In the present study, we assessed the effect of aging on memory length in cardiac rhythm. Results: There was a longer memory length in cardiac time-series of elderly subjects in comparison with younger adults for both decelerating and accelerating rare fluctuations in cardiac rhythm. Conclusion: The increased memory length of the cardiac time-series in elderly subjects may indicate reduced controllability of cardiovascular regulatory system.</div> Heart rate variability, Memory length, Controllability, Elderly 260 265 http://ppj.phypha.ir/browse.php?a_code=A-10-434-1&slc_lang=en&sid=1 Tara Ghafari t.ghafari@sbmu.ac.ir 3200319475328460018581 3200319475328460018581 No Department of Physiology, Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran Ava Ghafari ava.ghafari@mail.polimi.it 3200319475328460018582 3200319475328460018582 No Department of Electronic, Information and Bioengineering, Politecnico di Milano University, Milan, Italy Ali R. Mani a.r.mani@ucl.ac.uk 3200319475328460018583 3200319475328460018583 No Division of Medicine, UCL, London, UK Mohammad Reza Raoufy raoufy@modares.ac.ir 3200319475328460018584 3200319475328460018584 Yes Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran