Physiology and Pharmacology
Physiol Pharmacol
Medical Sciences
http://ppj.phypha.ir
32
journal32
24765236
24765244
10.61186/phypha
(previous ISSN: 17350581)
en
jalali
1378
1
1
gregorian
1999
4
1
3
1
online
1
fulltext
en
Primed-burst potentiation in adult rat visual cortex in vitro
Experimental research article
Experimental research article
<p> The effectiveness of θ pattern primed-bursts (PBs) on development of primed-burst (PB) potentiation was investigated in layer II/III of the adult rat visual cortex in vitro. Experiments were carried out in the visual cortical slices. Population excitatory post-synaptic potentials (pEPSPs) were evoked in layer II/III by stimulation of either white mater or layer IV. To induce long-term potentiation (LTP), eight episodes of PBs were delivered at 0.1 Hz. Regardless of stimulation site, field potential recorded in layer II/III consisted of two components: a short latency and high amplitude response called pEPSP<sub>1</sub>, and a long latency and low amplitude response called pEPSP<sub>2</sub>. The incidence of LTP produced by PBs of layer IV was higher than that of the white mater tetanization. In contrast, PBs of both layer IV and white mater reliably induced LTP of pEPSP<sub>2</sub> in layer II/III. It is concluded that PBs, as a type of activity pattern, of either white mater or layer IV can gain access to the modifiable synapses that are related to pEPSP<sub>2</sub> in layer II/III, but accessibility of the modifiable synapses that are related to pEPSP<sub>1</sub> depends on tetanization site. Relevancy of the results to the plasticity gate hypothesis is also discussed. </p><p> </p>
Primed-burst stimulation; Long term potentiation; Visual cortex; Layer IV; White mater
17
24
http://ppj.phypha.ir/browse.php?a_code=A-10-66-2&slc_lang=en&sid=1
Mahmood
Salami
320031947532846001846
320031947532846001846
Yes
Yaghub
Fathollahi
320031947532846001847
320031947532846001847
No
Fereshteh
Motamedi
320031947532846001848
320031947532846001848
No
Hossein
Esteky
320031947532846001849
320031947532846001849
No