en The effect of baclofen on the amount of milk production and its composition in Holstein cows Experimental research article Experimental research article <b><font face="TimesNewRomanPS-BoldMT" size="2"><p align="left">R Khakpai1</p></font><font face="TimesNewRomanPS-BoldMT" size="1">1 </font><font face="TimesNewRomanPS-BoldMT" size="2">and H Khazali</font><font face="TimesNewRomanPS-BoldMT" size="1">2</font><i><font face="TimesNewRomanPS-BoldItalicMT" size="2"><p align="left">1. Dept. Biology, Shaheed Beheshti University, Tehran, Iran.</p><p align="left">2. School of Agricultural sciences, Tarbiat Modares Univ. Tehran, Iran.</p></font><font face="TimesNewRomanPS-BoldMT" size="3"><p align="left">Abstract:</p></font><font face="TimesNewRomanPSMT" size="3"><p align="left">This research was done to determine the effect of baclofen - GABAB receptor agonist - on milk production and</p><p align="left">its composition.</p><p align="left">Twelve Holstein cows were divided to four groups, and in each groups 25, 50, 75 and 100 [mg/ (kg/b.w.)]</p><p align="left">baclofen were daily injected for four days. Cows were daily milked once a day in sterile milking room for ten</p><p align="left">days. Milk compositions were measured and recorded by Milko-Scan machinery. This study indicated that this</p><p align="left">treatments increased milk yield 17, 14, 15 and 16 percent, respectively (p<0.01). Protein, lactose and dry matter</p><p align="left">percent did not change significantly in any treatments. However, fat percent significantly increased (p<0.01).</p><p align="left">The results of this study suggest that baclofen increases milk production and fat percent however, it does not have</p><p align="left">any effect on other milk compositions.</p></font><b><font face="TimesNewRomanPS-BoldMT" size="3"><p align="left">Keywords: </p></font><font face="TimesNewRomanPSMT" size="3">GABA, Baclofen, Milk production, Milk composition, Dairy cows.</font></b></i></b> 163 166 http://ppj.phypha.ir/browse.php?a_code=A-10-1-19&slc_lang=en&sid=1