Physiology and Pharmacology

en Comparing the rate of carpal tunnel syndrome between 100 female students and 100 women with other occupation. Experimental research article Experimental research article H Nemati, A Nazari and E JalaliDept. of Physiology, Mashhad Univ. Med. Sciences, Mashhad, Iran.Abstract:Carpal tunnel syndrome (CTS) is a clinical entity characterized with pain, paresthesias, and numbness in the distributionof the median nerve with weakness and atrophy of the thenar muscle in advanced cases. It is universally accepted thatCTS is the clinical concordate of compression of the median nerve as it pass through the carpal channel. It is reported tobe the most common of the entrapment neuropathies. Increasing evidence suggests that occupational factors, includingforceful use of the hands repetitive use of wrist hands, and hand-arm vibration, are etiologic for CTS. When occurringas result of occupational exposure, the term “worked related carpal tunnel syndrome” is applied.In this study, we have randomly chosen and examined 100 university female students without any hard work and100 women with various occupations (dentist, carpet- weaver, tailor, surgeon, housewife, etc) for having CTSwith neurography.The neurography test showed that 3 female students and 29 working and housewife women were suffering fromthis syndrome (the ratio were about 1/10). Nerve conduction velocity have been decreased significantly and distalnerve latency have been increased significantly (p<0.001) in subjects with CTS. There was a direct relationshipbetween having CTS and wrist activity (χThe results showed that the rate of CTS increases in women with higher wrist activity.2= 25.1, p<0.001).Keywords: Peripheral neuropathy, Carpal tunnel syndrome, NCV. 189 193 http://ppj.phypha.ir/browse.php?a_code=A-10-1-22&slc_lang=en&sid=1