RT - Journal Article T1 - The effect of baclofen on growth hormone, thyroxine, and triiodothyronine in Holstein cows JF - Physiol-Pharmacol YR - 2003 JO - Physiol-Pharmacol VO - 7 IS - 1 UR - http://ppj.phypha.ir/article-1-431-en.html SP - 89 EP - 94 K1 - GABA; Baclofen; Growth hormone; Thyroxine; Triiodothyronine AB - In this research study, the effect of baclofen (GABAB receptor agonist) on mean concentration of growth hormone, thyroxine, and triiodothyronine was examined. For this purpose, twelve Holstein Cows were divided into four groups. Then, each cow received daily injection of 25, 50, 75, and l00 mg/kg of baclofen for a period of four days. Blood samples were daily collected at one time point for eight days. Growth hormone, thyroxine, and triiodothyronine concentrations of plasma samples were measured by RIA (Radioimmunoassay) method. The results showed that baclofen increased mean plasma concentration of growth hormone and thyroxine (p LA eng UL http://ppj.phypha.ir/article-1-431-en.html M3 ER -