AU - Masjedi, Fatemeh AU - Gol, Ali AU - Dabiri, Shahriar AU - Javadi, Abdoreza TI - Investigating the Preventive Effect of Garlic on Blood Glucose Levels and Histopathology of Pancreas in Streptozotocin-induced Diabetic Rats PT - JOURNAL ARTICLE TA - Physiol-Pharmacol JN - Physiol-Pharmacol VO - 13 VI - 2 IP - 2 4099 - http://ppj.phypha.ir/article-1-537-en.html 4100 - http://ppj.phypha.ir/article-1-537-en.pdf SO - Physiol-Pharmacol 2 ABĀ  - Introduction: The preventive antidiabetic effects of garlic juice on blood glucose levels and pancreas tissue was evaluated in STZ-induced diabetic rats. Methods: 40 male rats were divided into five groups of 8 rats each. 1) Normal group (N), 2) Normal+Garlic group (N+G) received 1 ml garlic juice/100g BW/day for 6 weeks, 3) Diabetic group (D) injected with streptozotocin (60 mg/kg BW,i.p.), 4) Diabetic + Garlic_before group (D+Gb) received garlic juice for 6 weeks, but at the end of third week, they were injected with STZ, 5) Diabetic+Garlic_after group (D+Ga) received garlic juice for 3 weeks, after they were injected with STZ. At the end of the experiment, serial sections of pancreas were prepared and stained with H&E for light microscope investigations. Results: Serum glucose levels were significantly increased (p CP - IRAN IN - Kerman - University of Shahid Bahonar- Faculty of Sciences- Department of Biology LG - eng PB - Physiol-Pharmacol PG - 179 PT - Experimental research article YR - 2009