@ARTICLE{Esmaeili Mahani, author = {Rezaei, Zahra and Nazerizadeh, Mohammad Reza and Seadat-Mahani, Mohammad Reza and Esmaeili Mahani, Saeed and }, title = {Oral administration of Teucrium polium extract ameliorates ovalbumin-induced allergy in rats}, volume = {17}, number = {3}, abstract ={Introduction: There are about 120 million people around the world who suffer from allergies. This is a huge number and all these individuals currently use anti-allergic drugs that are associated with numerous side effects. In order to find an appropriate complementary drug from traditional folk medicine, Teucrium polium was examined. Prednisolone was used as a control anti-allergic drug. Methods: Male Wistar rats were used and randomly divided into different experimental groups. Ovalbumin was used to induce allergy and sensitization challenge was confirmed by the presence of sneezing and changes in the level of eosinophils and IgE. Eight days after allergy induction, Teucrium polium (4, 8 and 12 mg/kg) was administrated orally for eight days. Blood samples were collected on day 16 and blood cell count and IgE concentration were determined. Positive control animals were given 2 mg/kg prednisolone in a similar manner. Results: The data showed that ovalbumin could induce sensitivity and increased eosinophils and IgE levels. Oral treatment with Teucrium polium showed significant decrease in the number of eosinophils (p }, URL = {http://ppj.phypha.ir/article-1-932-en.html}, eprint = {http://ppj.phypha.ir/article-1-932-en.pdf}, journal = {Physiology and Pharmacology}, doi = {}, year = {2013} }