Volume 27, Issue 1 (March 2023)
Physiol Pharmacol 2023, 27(1): 1-8 |
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Moallem S A, Asgharian Rezaee M, Mohammadpour A, Imenshahidi M. The effect of erythropoietin on cardiac and neurotoxicity induced by carbon monoxidepoisoning. Physiol Pharmacol 2023; 27 (1) :1-8
URL: http://ppj.phypha.ir/article-1-1704-en.html
URL: http://ppj.phypha.ir/article-1-1704-en.html
Abstract: (1647 Views)
Carbon monoxide (CO) intoxication is one of the most important poisonings related to high morbidity and mortality rate. The main treatment of CO poisoning is oxygen therapy using normobaric (NBO) or hyperbaric oxygen (HBO). However, more pharmaceutical agents are needed to improve CO poisoning treatment, especially in severe cases. Recently, erythropoietin (EPO) has been examined in several studies, showing a significant reduction in cardiac and neural sequels of CO poisoning.In this article, the effect of EPO on cardio and neurotoxicity of CO poisoning were reviewed. For this purpose, EPO effect on CO poisoning was searched in papers published until 2020 using Pubmed, Scopus, and google scholar. Only English papers on three main databases have been reviewed. The review of several animal and clinical studies have been shown that EPO administration after CO poisoning could improve neurological function and reduce CO-neurotoxicity significantly. Although there is good evidence of EPO effects on CO-induced-neurological sequelae, further clinical studies are needed to establish its benefit on CO intoxication.
Type of Manuscript: Mini-review |
Subject:
Pharmacokinetics/Dynamics
References
1. Alireza Nekoui G B. Erythropoietin and Non-Hematopoietic Effects: Review Article. AM J MED SCI 2017; 353: 76-81. [DOI:10.1016/j.amjms.2016.10.009]
2. Asgharian Rezaee M, Moallem S A, Imenshahidi M, Farzadnia M, Mohammadpour A H. Effects of erythropoietin on electrocardiogram changes in carbon monoxide poisoning: an experimental study in rats. Iran J Pharm Res 2012; 11: 1191-9.
3. Aydin A G K, Akhisaroglu M, Yorukogluc K, Gokmen N, Gonullu E. Erythropoietin exerts neuroprotective effect in neonatal rat model of hypoxic-ischemic brain injury. Brain Dev 2003; 25: 494-498. [DOI:10.1016/S0387-7604(03)00039-1]
4. Burger D, Xenocostas A, Feng Q P. Molecular basis of cardioprotection by erythropoietin. Curr Mol Pharmacol 2009; 2: 56-69. [DOI:10.2174/1874467210902010056]
5. Chiew A L, Buckley N A. Carbon monoxide poisoning in the 21st century. Crit. Care 2014; 18: 221. [DOI:10.1186/cc13846]
6. Choi I S. Parkinsonism after carbon monoxide poisoning. Eur Neurol 2002; 48: 30-3. [DOI:10.1159/000064954]
7. Dame C J S, Christensen RD. The biology of erythropoietin in the central nervous system and its neurotrophic and neuroprotective potential. Biol Neonate 2001; 79: 228-235. [DOI:10.1159/000047097]
8. Danold S Silerberg D w, Miriam Blum, Adian Laina, David Sheps, Gad Keren, Doron Schwartz. Erythropoiein in heart failure Semin nephrol 2005; 25: 3997-403. [DOI:10.1016/j.semnephrol.2005.05.009]
9. Dubrey S W, Chehab O, Ghonim S. Carbon monoxide poisoning: an ancient and frequent cause of accidental death. Br J Hosp Med (Lond) 2015; 76: 159-62. [DOI:10.12968/hmed.2015.76.3.159]
10. Eichhorn L, Thudium M, Jüttner B. The Diagnosis and Treatment of Carbon Monoxide Poisoning. Dtsch Arztebl Int 2018; 115: 863-870. [DOI:10.3238/arztebl.2018.0863]
11. EJ L. carbon monoxide poisoning. In: Shannon MW BS, Burns M, editor. Haddad and Winchester's clinical management of poisoning and drug overdose. Philadelphia: Saunders/Elsevier, 2007: 1297-1307. [DOI:10.1016/B978-0-7216-0693-4.50092-X]
12. Florian Simon N F, Wiebke Ibing, Hubert Schelzig, Artis Knapsis. Neurotherapeutic potential of erythropoietin after ischemic injury of the central nervous system. Neural Regen Res 2019; 14: 1309-1312. [DOI:10.4103/1673-5374.253507]
13. François Roubille F P, Stéphanie Barrère-Lemaire, Florence Leclercq, Christophe Piot, Ekaterini A. Kritikou, Eric Rhéaume, David Busseuil, Jean-Claude Tardif. What is the Role of Erythropoietin in Acute Myocardial Infarct? Bridging the Gap Between Experimental Models and Clinical Trials. Cardiovasc Drugs Ther 2013; 27: 315-331. [DOI:10.1007/s10557-013-6461-1]
14. Gandini C, Castoldi A F, Candura S M, Locatelli C, Butera R, Priori S, et al. Carbon monoxide cardiotoxicity. J Toxicol Clin Toxicol 2001; 39: 35-44. [DOI:10.1081/CLT-100102878]
15. Ghezzi P, Brines M. Erythropoietin as an antiapoptotic, tissue-protective cytokine. Cell Death Differ 2004; 11: S37-S44. [DOI:10.1038/sj.cdd.4401450]
16. Guzman J A. Carbon monoxide poisoning. Crit Care Clin 2012; 28: 537-48. [DOI:10.1016/j.ccc.2012.07.007]
17. Hannelore Ehrenreich, Martin Hasselblatt, Christoph Dembowski, Lukas Cepek, Piotr Lewczuk, Michael Stiefel, et al. Erythropoietin Therapy for Acute Stroke Is Both Safe and Beneficial. Mol. Med 2002; 8: 495-505. [DOI:10.1007/BF03402029]
18. Henry C R, Satran D, Lindgren B, Adkinson C, Nicholson C I, Henry T D. Myocardial injury and long-term mortality following moderate to severe carbon monoxide poisoning. Jama 2006; 295: 398-402. [DOI:10.1001/jama.295.4.398]
19. Jelkmann W. Molecular biology of erythropoietin. Intern. Med 2004; 43: 649-659. [DOI:10.2169/internalmedicine.43.649]
20. Joyeux-Faure M, Godin-Ribuot D, Ribuot C. Erythropoietin and myocardial protection: what's new. Fundam Clin Pharmacol 2005; 19: 439-46. [DOI:10.1111/j.1472-8206.2005.00347.x]
21. Kao H-W, Cho N-Y, Hsueh C-J, Chou M-C, Chung H-W, Liou M, et al. Delayed Parkinsonism after CO Intoxication: Evaluation of the Substantia Nigra with Inversion-Recovery MR Imaging. Radiology 2012; 265: 215-221. [DOI:10.1148/radiol.12112714]
22. Katavetin P, Tungsanga K, Eiam-Ong S, Nangaku M. Antioxidative effects of erythropoietin. Kidney Int 2007; 72: S10-S15. [DOI:10.1038/sj.ki.5002482]
23. Kaveh Abri Aghdam M S S, Khalil Ghasemi Falavarjani. Erythropoietin in ophthalmology: A literature review. J. Curr. Ophthalmol. 2016; 28: 5-11. [DOI:10.1016/j.joco.2016.01.008]
24. Kinoshita H, Türkan H, Vucinic S, Naqvi S, Bedair R, Rezaee R, et al. Carbon monoxide poisoning. Toxicol. Rep 2020; 7: 169-173. [DOI:10.1016/j.toxrep.2020.01.005]
25. Lai C-Y, Chou M-C, Lin C-L, Kao C-H. Increased risk of Parkinson disease in patients with carbon monoxide intoxication: a population-based cohort study. Medicine 2015; 94: e869-e869. [DOI:10.1097/MD.0000000000000869]
26. Lawrence T. The nuclear factor NF-kappaB pathway in inflammation. Cold Spring Harb Perspect Biol 2009; 1: 1-10. [DOI:10.1101/cshperspect.a001651]
27. Li Y, Hu X, Lu Z. Erythropoietin in the treatment of encephalopathy associated with carbon monoxide poisoning. Prog Neuropsychopharmacol Biol Psychiatry 2009; 33: 735-8. [DOI:10.1016/j.pnpbp.2009.03.014]
28. Lippi G, Rastelli G, Meschi T, Borghi L, Cervellin G. Pathophysiology, clinics, diagnosis and treatment of heart involvement in carbon monoxide poisoning. Clin Biochem 2012; 45: 1278-85. [DOI:10.1016/j.clinbiochem.2012.06.004]
29. Mastromarino V, Musumeci M B, Conti E, Tocci G, Volpe M. Erythropoietin in cardiac disease: effective or harmful? J Cardiovasc Med (Hagerstown) 2013; 14: 870-8. [DOI:10.2459/JCM.0b013e328362c6ae]
30. Moallem S A, Mohamadpour A H, Abnous K, Sankian M, Sadeghnia H R, Tsatsakis A, et al. Erythropoietin in the treatment of carbon monoxide neurotoxicity in rat. Food Chem Toxicol 2015; 86: 56-64. [DOI:10.1016/j.fct.2015.09.015]
31. Nguyen A Q, Cherry B H, Scott G F, Ryou M G, Mallet R T. Erythropoietin: powerful protection of ischemic and post-ischemic brain. Exp Biol Med (Maywood) 2014; 239: 1461-75. [DOI:10.1177/1535370214523703]
32. Oh S, Choi S-C. Acute carbon monoxide poisoning and delayed neurological sequelae: a potential neuroprotection bundle therapy. Neural Regen Res 2015; 10: 36-38. [DOI:10.4103/1673-5374.150644]
33. Pang L, Bian M, Zang X X, Wu Y, Xu D H, Dong N, et al. Neuroprotective effects of erythropoietin in patients with carbon monoxide poisoning. J Biochem Mol Toxicol 2013; 27: 266-71. [DOI:10.1002/jbt.21484]
34. Pang L, Zhang N, Dong N, Wang D W, Xu D H, Zhang P, et al. Erythropoietin Protects Rat Brain Injury from Carbon Monoxide Poisoning by Inhibiting Toll-Like Receptor 4/NF-kappa B-Dependent Inflammatory Responses. Inflammation 2016; 39: 561-8. [DOI:10.1007/s10753-015-0280-4]
35. Paschos N, Lykissas M G, Beris A E. The role of erythropoietin as an inhibitor of tissue ischemia. Int J Biol Sci 2008; 4: 161-8. [DOI:10.7150/ijbs.4.161]
36. Peng B, Kong G, Yang C, Ming Y. Erythropoietin and its derivatives: from tissue protection to immune regulation. Cell Death Dis 2020; 11: 79. [DOI:10.1038/s41419-020-2276-8]
37. Prockop L D, Chichkova R I. Carbon monoxide intoxication: an updated review. J Neurol Sci 2007; 262: 122-30. [DOI:10.1016/j.jns.2007.06.037]
38. Rezaee M A, Moallem S A, Mohammadpour A H, Mahmoudi M, Sankian M, Farzadnia M, et al. Histopathological study of erythropoietin protective effect on carbon monoxide-induced cardiotoxicity in rat. Iran J Basic Med Sci 2017; 20: 1189-1193.
39. Rezaee M A, Mohammadpour A H, Imenshahidi M, Mahmoudi M, Sankian M, Tsarouhas K, et al. Protective effect of erythropoietin on myocardial apoptosis in rats exposed to carbon monoxide. Life Sci 2016; 148: 118-24. [DOI:10.1016/j.lfs.2016.02.007]
40. Rose J J, Wang L, Xu Q, McTiernan C F, Shiva S, Tejero J, et al. Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy. Am J Respir Crit Care Med 2017; 195: 596-606. [DOI:10.1164/rccm.201606-1275CI]
41. S. Shahsavand S M, A. Mohhamadpour. Evaluation of erythropoietin effect on cellular neurotoxicity after carbon monoxide poisoning in rat. Res Pharm Sci 2012; 7: 5.
42. Santhanam A V R, d'Uscio L V, Katusic Z S. Cardiovascular effects of erythropoietin an update. Adv. Pharmacol 2010; 60: 257-285. [DOI:10.1016/B978-0-12-385061-4.00009-X]
43. Sasaki R. Pleiotropic functions of erythropoietin. Intern Med 2003; 42: 142-9. [DOI:10.2169/internalmedicine.42.142]
44. Seyed Mohammad Hosseininejad H A, Iraj Goli Khatir, Seyed Khosro Ghasempouri, Ali Jabbari, Mahmoud Khandashpour. Carbon monoxide poisoning in Iran during 1999-2016: A systematic review and metaanalysis. J Forensic Leg Med 2018; 53: 87-96. [DOI:10.1016/j.jflm.2017.11.008]
45. Shahsavand S, Mohammadpour A H, Rezaee R, Behravan E, Sakhtianchi R, Moallem S A. Effect of Erythropoietin on Serum Brain-derived Biomarkers after Carbon Monoxide Poisoning in Rats. Iran J Basic Med Sci 2012; 15: 752-8.
46. Shi Y, Rafiee P, Su J, Pritchard K A, Jr., Tweddell J S, Baker J E. Acute cardioprotective effects of erythropoietin in infant rabbits are mediated by activation of protein kinases and potassium channels. Basic Res Cardiol 2004; 99: 173-82. [DOI:10.1007/s00395-004-0455-x]
47. Weaver L K. Clinical practice. Carbon monoxide poisoning. N Engl J Med 2009; 360: 1217-25. [DOI:10.1056/NEJMcp0808891]
48. Wu P E, Juurlink D N. Carbon monoxide poisoning. CMAJ 2014; 186: 611-611. [DOI:10.1503/cmaj.130972]
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