Volume 27, Issue 4 (December 2023)                   Physiol Pharmacol 2023, 27(4): 387-391 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sharma B, Shrivastava S K, Shukla N, Dave R, Shrivastava A. Assessment of defects in peripheral and central transmission of auditory Assessment of Defects in Peripheral and Central Transmission of Auditory Pathway Using Brainstem Auditory Evoked Potentials in Preterm Babies pathway by Brainstem Audiometry Evoked Potentials in preterm babies. Physiol Pharmacol 2023; 27 (4) : 4
URL: http://ppj.phypha.ir/article-1-2010-en.html
Abstract:   (967 Views)

Introduction: Brainstem Auditory Evoked Potentials (BAEP) play a crucial role in pediatric audiology, particularly for evaluating auditory function in children when behavioral testing is not possible. It serves as a valuable tool for assessing the auditory pathways of the brainstem.
Methods: This study aims to compare latencies of wave I and wave III through Brainstem Auditory Evoked Potential (BAEP) in preterm babies (32 to 36 weeks) against age specific normal responses. The goal is to identify potential hearing impairment indicated by any increased BAEP latencies in wave I and wave III.
Results: The study involved 50 preterm newborns divided into three groups based on gestational age: Group A (32 weeks, n=12), Group B (34 weeks, n=18), and Group C (36 weeks, n=20). The infants underwent BAEP testing using the RMS EMG EP MARK-II machine at the Neurophysiology Unit of the Department of Physiology, Gandhi Medical College, Bhopal. Data interpretation involved comparing the obtained values to established normal values.
Conclusion: The study observed increased absolute peak latencies of wave I and III in preterm babies compared to normal term infants, suggesting defects in peripheral transmission and improper myelination of the BAEP pathway. When comparing between groups, significant differences were found in the absolute latencies of waves I and III in both ears between group 1 and groups 2 and 3. Additionally, significant differences were noted in the latency of waves I and III in the right ear between group 2 and group 3.

Article number: 4
Full-Text [PDF 646 kb]   (274 Downloads)    

References
1. Agrawal VK, Shukla R, et al. Brainstem auditory evoked response in newborns with hyperbilirubinemia. Indian Pediat 1998; 35: 513-18.
2. Ballard JL, Khoury JC, Wedig K, Wang L, Eilers-Walsman BL, Lipp R. New Ballard score, expanded to include extremely premature infants. J Pediatr 1991; 119: 417-423.
3. Bilgen H, Akman I, Ozek E, Kulekel S, Rahmi ORS, Carman F Auditory brainstem response screening for hearing loss in high risk neonates. Turk J Med Sci 2000; 30: 479-82.
4. Despland PA. Maturational changes in the auditory system as reflected in human brainstem evoked responses. Dev Neurosci 1985; 7: 73-80.
5. Dobbing J, Sands J. Quantitative growth and development of human brain. Arch Dis Child 1973; 48: 757-67.
6. Eggermont JJ, Salamy A. Maturational time course for the ABR in preterm and full term Infants Hear Res 1988; 33: 35-48.
7. Engle WA, Tomashek KM, Wallman C. “Late-preterm” infants: a population at risk. J Pediatr 2007; 120(6): 1390-401.
8. Goldstein PJ, Krumholz A, Felix JK, Shannon D, Carr RF. Brainstem evoked response in neonates. AJOG 1979; 135: 622-8.
9. Jiang ZD, Wilkinsons AR. Normal brainstem responses in moderately preterm infants. Acta Pediatr 2008; 97(10): 1366-9.
10. Joint Committee on Infant Hearing. American Academy of Pediatrics. American Speech - Language - Hearing Association. Directors of speech and hearing programs in State Health and Welfare Agencies. Year 2007 Position statement: Principles and Guidelines for early hearing detection and intervention programs. Pediatrics. 2007; 120 (4) 898 - 921.
11. Kilic I, Karahan H, Kurt T, Ergin H, Sahiner T. Brainstem evoked response audiometry and risk factors in premature infants. Marmara Med J 2007; 20(1):21-8.
12. Maisels JM, Avery GB, Fletcher MA, MacDonald MG. Neonatology, pathophysiology and management of the newborn. Philadelphia JB Lippincott Co 1994. 630-725.
13. Norman MG. Perinatal brain damage. Per sped Pediatric Pathol 1975; 4: 41-92.
14. Pasman JW, Retteveel JF, de Graaf R, Maassen B, Visco YM. The effects of early and late preterm birth on brainstem and middle-latency auditory evoked responses in children with normal neurodevelopment. J Clin Neurophysiol 1996; 13(3): 234-41.
15. Raquel LC, Maria F, Colella DS. Auditory Brainstem Evoked Response: response patterns of fullterm and premature infants. Braz J Otorhinolaryngol 2010; 76(6): 729-38.
16. Roopkala MS, Dayananda G, Manjula P, Konde AS, Acharya PT, Srinivasa R, et al. A comparative study of brainstem auditory evoked potentials in preterm and full-term infants. Indian J Physiol Pharmacol 2011; 55(1): 44-52.
17. Salamy A. Maturation of the auditory brainstem response from birth to early childhood. J Clin Neurophysiol 1984; 1: 293-329.
18. Shah SN, Bhargava VK, Johnson RC, McKean CM. Latency changes in brainstem auditory evoked potentials associated with impaired brain myelination. Exp Neurol 1978; 58: 111-8.
19. Venkatesh LT, Brid SV Shivagirao. Brainstem evoked auditory response in preterm and full term infants. NJPPP 2005; 5: 56-59.
20. Yakovlev PI, Lecour A. The myelogenetic cycles of regional maturation of the brain. Regional development of the brain in early life. Philadelphia 1967; 3-69.

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.