Volume 10, Issue 1 (Spring 2006)
Physiol Pharmacol 2006, 10(1): 79-85 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Sadat Rezaeian Z, Torkaman G, Nad-ali F, Ravanbod R, Nejatian M, Gosheh B et al . Effect of Aerobic Training on Coagulant Activity in Healthy Young Men. Physiol Pharmacol 2006; 10 (1) :79-85
URL: http://ppj.phypha.ir/article-1-83-en.html
URL: http://ppj.phypha.ir/article-1-83-en.html
Zahra Sadat Rezaeian 
, Giti Torkaman , Fatemeh Nad-ali , Roya Ravanbod , Mostafa Nejatian , Babak Gosheh , Mohammad Ali Broumand
, Giti Torkaman , Fatemeh Nad-ali , Roya Ravanbod , Mostafa Nejatian , Babak Gosheh , Mohammad Ali Broumand
Abstract: (12743 Views)
Introduction: Effects of exercise on different body systems, especially cardiovascular and musculoskeletal
systems are evidenced. There is a dynamic homeostatic balance between coagulation and fibrinolysis in normal
circulation. Effect of exercise and training on this homeostatic balance has been studied extensively but there are
a few studies with regards to analysis of the effects of training programs on coagulation factors. Therefore, we
studied the effect of 8 weeks aerobic training program on coagulation factors in healthy young men.
Methods: Subjects were 16 young sedentary men without any history of cardiac, coagulation or respiratory
problems in their first-degree family and their cardiovascular health was confirmed by a cardiac specialist. We
randomly selected 10 of them as test group who participated in a submaximal training program on cycle ergometer
3 times a week for 8 weeks. Each training session consisted of 1 minute warm up, 15 minute aerobic exercise, 8
minute active recovery and 45 minute passive recovery. The remaining individuals were controls and restrained
from exercise in this period. Before and after training period, response of coagulation system to a submaximal
exercise on cycle ergometer was studied by a standardized Ergometery test.
Results: Basic value of coagulation variables were the same in both groups before and after training period.
After 8 weeks, there was no significant change in anthropometric variables in both groups and so the change in
blood variables was independent to physical characteristics of individuals. After 8 weeks of aerobic training,
FVIII:c, FIX:c, Fbg and vwF:ac increased in response to exercise that was statistically significant only in Tr
group. There was a significant decrease in vwF:ag, aPTT, FVII in this group. We conclude that 8 weeks aerobic
training enhances the response of FVIII:c, FIX:c, FVII:c, vwF:ac, Fbg and aPTT to exercise but has no effect on
the response of vwF:ag and PT.
Conclusion: It seems that the recommended aerobic exercise training protocol will enhance the response of
coagulation factors to one session of Ergometric exercise in healthy young men. Due to the importance of blood
homeostasis and the effects of coagulation and fibrinolysis imbalance, any type of physical activity especially any
exercise program should be analyzed carefully for its effect on haemostatic balance.
Type of Manuscript: Experimental research article |
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
